this is the part of the peptide world that i think could get really weird over the next 10-20 years
right now "longevity" is mostly indirect
better metabolic health
mitochondrial stuff
inflammation
tissue repair
senescent cells
telomeres etc
but what happens when trials get good enough that a drug company can actually say something like:
"people taking X aged 12% slower than placebo over 3 years"
not saying any peptide can do this today btw. we're definitely not there yet
and the biggest problem is probably figuring out what "12% slower aging" even means
an aging clock going backwards sounds amazing... but does that actually mean you live longer? stay healthy longer? get cancer later? maintain strength longer?
i'd imagine eventually you'd need multiple things all pointing the same direction... epigenetic/protein clocks, organ function, physical performance, disease rates etc
there's already research around peptides / peptide-like compounds targeting different pieces of aging biology, but most of it seems miles away from being able to make a claim like "slows human aging by X%"
still...
if someone eventually pulls that off, i honestly think it could be a much bigger moment than GLP-1s
weight loss is obviously huge
but "take this and biologically age 10% slower" is a completely different level
curious what people think
would you even trust a "% slower aging" number?
and what would you need to see before you believed it... aging clocks? 5-10 year trial? actual reduction in age-related disease?
also what % would even be meaningful?
5%? 10%? 20%?